When an individual at risk for forming a thrombus is treated with anticoagulant medication, the International Normalized Ratio (INR) must be measured regularly. We explore the conditions under which an injury-induced thrombus may form in vivo but not in vitro. We extend previous models and present numerical simulations that compare scenarios in which drug doses and flow rates are modified. Our results indicate that traditional INR measurements may not accurately reflect in vivo clotting times.
Short Bio: Yanping Ma obtained her PhD in math at Penn State University with minor in statistics, and her B.S. from the University of Science and Technology of China in math and applied math. She is currently working at Loyola Marymount University as an assistant professor. Her research interest is in bio mathematics modeling and math education.